Upstream Binding Protein 1 (Lbp-1A) (UBP1) Antibody
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Description
Upstream Binding Protein 1 (Lbp-1A) Antibody is a Rabbit Polyclonal antibody against Upstream Binding Protein 1 (Lbp-1A).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Upstream Binding Protein 1 (Lbp-1A) (UBP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NZI7 |
| Gene ID | 7342 |
| NCBI Accession | NP_001121632.1, NM_001128160.1, NP_001121633.1, NM_001128161.1 |
| OMIM | 609784 |
| Background | Antibody anti-UBP1 |
| Status | RUO |
Descripción
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UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
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