UniQ PIIINP RIA

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

proveedor

Aidian

reference

68570

Tested Applications

RIA

reactivity

human

status

CE Marked

clonality

Descripción

UniQ PIIINP RIA is a quantitative radioimmunoassay designed for measurement of the concentration of intact aminoterminal propeptide of type III procollagen in human serum


UniQ PIIINP RIA es un radioinmunoensayo cuantitativo diseñado para medir la concentración del propéptido aminoterminal intacto de tipo III de la procolágeno en suero humano.

Background

PIIINP - aminoterminal propeptide of type III procollagen - is liberated into the circulation during soft tissue formation. Changes in PIIINP levels reflect the involvement and altered metabolism of type III collagen, which is common in many connective tissue disorders. PIIINP can be used to assess and monitor fibrotic processes in liver diseases, thus avoiding the need for liver biopsies. It is also useful for monitoring growth hormone therapy in children with growth disorders. PIIINP gives prognostic information on cardiac disease and reflects the healing process.


PIIINP, propeptido aminoterminal del colágeno tipo III, se libera en la circulación durante la formación de tejido blando. Los cambios en los niveles de PIIINP reflejan la participación y el metabolismo alterado del colágeno tipo III, lo que es común en muchos trastornos del tejido conectivo. El PIIINP se puede utilizar para evaluar y monitorear procesos fibróticos en enfermedades hepáticas, evitando así la necesidad de biopsias hepáticas. También es útil para monitorear la terapia con hormona de crecimiento en niños con trastornos del crecimiento. El PIIINP proporciona información pronóstica sobre enfermedades cardíacas y refleja el proceso de cicatrización.

Características del producto

category

RIA Kits


size 1

100 test


storage

2 – 8 °C


test range

1.0‒50 µg/l.


detection method

UniQ PIIINP RIA kit is based on the competitive radioimmunoassay technique. A known amount of labelled PIIINP and an unknown amount of unlabelled PIIINP in the sample compete for a limited number of high-affinity binding sites on the antibody. After separating the free antigen, the amount of labelled PIIINP in the sample tube is inversely proportional to the amount of PIIINP in the sample. The concentrations in unknown samples are obtained from a calibration curve.


assay data

PIIINP: no cross-reactivity with PINP.


availability

Inmediate


dry ice

No


note

200 µl serum


reseach area

Colágeno


status

CE Marked


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