Tyrosine-Protein Kinase CSK (CSK) Antibody
383.5€ (100 µl)
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Name
Tyrosine-Protein Kinase CSK (CSK) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx015831
Tested Applications
ELISA, WB, IF/ICC, FCM
Description
Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine.Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK.This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive.The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk.Tissue specificity: Expressed in lung and macrophages.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tyrosine-Protein Kinase CSK (CSK) Immunogen: Purified recombinant fragment of human CSK expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human, Mouse, Monkey, Rat |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 50 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 1445 |
| Background | Antibody anti-CSK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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