Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)
169€ (20 µg)
169€ (20 µg)
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935106861
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name
Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx314741
Descripción del producto
AGTR1 Antibody (FITC) is a Rabbit Polyclonal against AGTR1 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| OMIM | 106165 |
| Alias | AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor |
| Availability | Shipped within 5-10 working days. |
| Background | Antibody anti-AGTR1 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Category | Primary Antibodies |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Dry Ice | No |
| Form | Liquid |
| Gene ID | 185 |
| Host | Rabbit |
| Immunogen Target | Type-1 Angiotensin II Receptor (AGTR1) |
| Isotype | IgG |
| Name | Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC) |
| Note | Concentration: 0.25 mg/ml - |
| Price | 169 |
| Provider | Abbexa |
| Purification | Purified by Protein G. |
| Purity | > 95% |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx314741 |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Status | RUO |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| UniProt ID | P30556 |
Descripcion del producto en español
Background en español
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
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