Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
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169€ (20 µg)

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935106861
info@markelab.com
name
Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx314741

Description

AGTR1 Antibody (FITC) is a Rabbit Polyclonal against AGTR1 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Type-1 Angiotensin II Receptor (AGTR1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P30556
Gene ID
185
OMIM
106165
Alias
AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor
Background
Antibody anti-AGTR1
Status
RUO
Note
Concentration: 0.25 mg/ml - 

Descripción

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

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