Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
Type-1 Angiotensin II Receptor (AGTR1) Antibody (FITC)

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µg)

Antibody anti-AGTR1

proveedor

Abbexa

reference

abx314741

Tested Applications

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

AGTR1 Antibody (FITC) is a Rabbit Polyclonal against AGTR1 conjugated to FITC.

Background

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Type-1 Angiotensin II Receptor (AGTR1)

host

Rabbit

isotype

IgG

conjugation

FITC

form

Liquid

purity

> 95%

purification

Purified by Protein G.

recommended dilution

Optimal dilutions/concentrations should be determined by the end user.

buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.

size 1

20 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.

or code

AGTR1

dry ice

No

availability

Shipped within 5-10 working days.

alias

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor

uniprot id

https://www.uniprot.org/uniprotkb/P30556

gene id

https://www.ncbi.nlm.nih.gov/gene/185

note

Concentration: 0.25 mg/ml -

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