Human AGTR1(Type-1 angiotensin II receptor) ELISA Kit

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
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935106861
info@markelab.com
name
Human AGTR1(Type-1 angiotensin II receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1872

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Size 1
96T
Sample Type
Serum,Plasma,Tissue homogenates,Other biological fluids
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
P30556
Alias
AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor
Background
Elisa Kits AGTR1
Status
RUO

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

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