Type-1 Angiotensin II Receptor (AGTR1) Antibody

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
Type-1 Angiotensin II Receptor (AGTR1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

299€ (50 µl)

Antibody anti-AGTR1

proveedor

Abbexa

reference

abx402184

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

Type-1 Angiotensin II Receptor (AGTR1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human AGTR1.

Background

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

Características del producto

category

Primary Antibodies

clonality

Monoclonal

reactivity

Human

immunogen target

Type-1 Angiotensin II Receptor (AGTR1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

expression

Recombinant

purification

Purified by affinity chromatography.

recommended dilution

WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

size 1

50 µl

size 2

100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

AGTR1

dry ice

No

availability

Shipped within 5-10 working days.

alias

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor

uniprot id

https://www.uniprot.org/uniprotkb/P30556

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