Type-1 Angiotensin II Receptor (AGTR1) Antibody

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
Type-1 Angiotensin II Receptor (AGTR1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

357.5€ (100 µg)

Antibody anti-AGTR1

proveedor

Abbexa

reference

abx037681

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Rabbit Polyclonal against the AGTR1 protein.

Background

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Human

immunogen target

Type-1 Angiotensin II Receptor (AGTR1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Lyophilized

tested applications

ELISA, WB

purification

Purified by antigen affinity column chromatography.

recommended dilution

ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Prior to lyophilization: 1% BSA and 0.02% NaN3.

size 1

100 µg

size 2

1 mg

storage

Store at -20 °C. Avoid repeated freeze/thaw cycles.

or code

AGTR1

dry ice

No

availability

Shipped within 7-15 working days.

alias

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor

uniprot id

https://www.uniprot.org/uniprotkb/P30556

note

Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

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