Tumor Necrosis Factor Receptor Protein
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Description
Tumor Necrosis Factor Receptor Protein is a recombinant cytokine.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | TNFR |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 97% (SDS-PAGE and RP-HPLC) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P19438 |
| Gene ID | 7132 |
| OMIM | 142680 |
| Background | Protein TNFR |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
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Tumor Necrosis Factor Receptor Protein
Tumor Necrosis Factor Receptor Protein is a recombinant cytokine.
Ver ProductoTumor Necrosis Factor Receptor Protein
Tumor Necrosis Factor Receptor Protein is a recombinant cytokine.
Ver Producto