Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody (Biotin)
559€ (100 µg)
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935106861
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name
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx239851
tested applications
ELISA
Description
TNFSF14 Antibody is a Rabbit Polyclonal (
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43557 |
| Alias | Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand |
| Background | Antibody anti-TNFSF14 |
| Status | RUO |
| Note | - Validity: 12 months. |
Descripción
TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.
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