Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) Antibody
780€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx174973
Tested Applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Tumor necrosis factor ligand superfamily member 13,APRIL,CD256,TALL2,ZTNF2,TALL-2,TNLG7B,TRDL-1,A proliferation-inducing ligand,TNF- and APOL-related leukocyte expressed ligand 2,TNF-related death ligand 1 |
| Background | Antibody anti-TNFSF13 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TNFSF13, also known as APRIL (A Proliferation-Inducing Ligand), is a protein within the tumor necrosis factor (TNF) superfamily involved in immune system regulation, especially in B-cell survival, proliferation, and antibody production. This ligand, encoded by the TNFSF13 gene, binds to specific receptors on immune cells, including TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor) and BCMA (B-Cell Maturation Antigen), to initiate signaling pathways that promote immune responses and sustain humoral immunity. APRIL, along with BAFF (B-cell Activating Factor), another TNF family ligand, is essential for adaptive immunity, supporting B cell maturation and differentiation. APRIL is mainly expressed by myeloid cells, such as dendritic cells and macrophages, and some types of lymphoid cells. Beyond its role in immune cell survival, APRIL has clinical significance, as its overexpression has been associated with autoimmune diseases, certain cancers, and inflammatory disorders. The APRIL/BAFF signaling pathways represent crucial targets for immunotherapy, especially in treating autoimmune diseases and B-cell malignancies.
Productos relacionados
Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) Antibody
TNFSF13 Antibody is a Rabbit Polyclonal antibody against TNFSF13. The protein encoded by this gene is a member of the tu…
Ver producto
Human Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) Protein
Human Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) is a recombinant Human protein expressed in E. coli.…
Ver producto
Mouse Tumor Necrosis Factor Ligand Superfamily Member 13 / CD256 (TNFSF13) Protein
Mouse Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) is a recombinant Mouse protein expressed in E. coli.…
Ver producto