Tubulin Alpha-1A Chain (TUBA1A) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Tubulin Alpha-1A Chain (TUBA1A) Antibody is a Rat Monoclonal against Tubulin Alpha-1A Chain (TUBA1A).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tubulin Alpha-1A Chain (TUBA1A) |
| Host | Rat |
| Reactivity | Human, Mouse, Rat, Bird, Yeast |
| Recommended Dilution | FCM: 8-12 μg/ml, WB: 1-2 μg/ml, ICC: 4-8 μg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone ID | F214 |
| Purification | Purified by Protein G affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q71U36 |
| Gene ID | 7277 |
| Background | Antibody anti-TUBA1A |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
FITC Anti-Acetylated tubulin (Lys40)
Ver ProductoAcetylated tubulin (Lys40) antibody
Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin; it does not recognize non-acetylated tubulin.
Ver Productoalpha Tubulin antibody
Alpha 1a Tubulin is also known as Alpha-tubulin 3. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Alpha 1a Tubulin is expressed at a high level in fetal brain.
Ver Producto