TSPY Like 2 (TSPYL2) Antibody
292.5€ (80 µl)
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Name
TSPY Like 2 (TSPYL2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034821
Tested Applications
ELISA, WB
Description
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: TSPY Like 2 (TSPYL2) Immunogen: KLH-conjugated synthetic peptide between 380-409 amino acids from the Central region of human TSPYL2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 79.4 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H2G4 |
| NCBI Accession | NP_071400.1 |
| Alias | CDA1,CTCL,NP79,TSPX,CINAP,DENTT,SE204,HRIHFB2216,Testis-specific Y-encoded-like protein 2,TSPY-like protein 2,Cell division autoantigen 1,Nuclear protein of 79 kDa |
| Background | Antibody anti-TSPYL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TSPY like 2 (TSPYL2) is a protein that is part of the TSPY gene family, known for its roles in regulating gene expression and cellular differentiation TSPYL2 is implicated in modulating transcriptional processes, particularly in tissues involved in reproductive development and stem cell maintenance It has been suggested that TSPYL2 may have a role in cell cycle regulation and apoptosis, although its exact functions in different tissues are still under investigation TSPYL2’s expression is found in various tissues, particularly in the brain and testis, and its expression levels may be crucial for tissue homeostasis and cell differentiation In cancer, aberrations in TSPYL2 expression may influence tumor progression, with some studies indicating its potential as a tumor suppressor Protein interactions with transcription factors and chromatin-modifying complexes suggest that TSPYL2 may play a role in maintaining genomic stability and regulating cellular responses to stress, contributing to its involvement in cellular integrity and disease prevention
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