TrkA (pY490) Antibody
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935106861
info@markelab.com
Precio
200€ (20 µl)
Antibody anti-NTRK1
proveedor
Abbexareference
abx123277Tested Applications
WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
TrkA (pY490) Antibody is a Rabbit Polyclonal Antibody against TrkA (pY490).
Background
Neurotrophic receptor tyrosine kinase 1 (NTRK1) is an essential receptor that binds with nerve growth factor (NGF), initiating critical signaling cascades required for the survival, differentiation, and functional maintenance of neurons, particularly within the peripheral nervous system. Beyond supporting neuronal growth, NTRK1 contributes to injury responses, helping facilitate neuronal repair and regeneration. Dysregulation or mutations in NTRK1 have been implicated in neurodegenerative diseases, such as Charcot-Marie-Tooth disease, as well as in certain cancers, making it a significant target for therapeutic research and drug development efforts.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
TrkA (pY490)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB
purification
Purified by affinity chromatography.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
NTRK1
dry ice
No
availability
Shipped within 5-10 working days.
alias
MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor
uniprot id
NCBI accession
NP_001012331.1
note
This product is for research use only.
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