Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr680/Y681 (NTRK1 pY680/Y681) Cell ELISA Kit

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr680/Y681 (NTRK1 pY680/Y681) Cell ELISA Kit
546€ (192 tests)

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Name
Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr680/Y681 (NTRK1 pY680/Y681) Cell ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx596063
Tested Applications
ELISA

Description

Trk A (pY680+Tyr681) Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr680/Y681 (NTRK1 pY680/Y681)
Reactivity
Human, Mouse, Rat
Detection Method
Fluorometric
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
192 tests
Tested Applications
ELISA
Availability
Shipped within 1-2 weeks.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P04629
Gene ID
4914
OMIM
164970
Alias
MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor
Background
Elisa Kits for: NTRK1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Background

Neurotrophic receptor tyrosine kinase 1 (NTRK1) is an essential receptor that binds with nerve growth factor (NGF), initiating critical signaling cascades required for the survival, differentiation, and functional maintenance of neurons, particularly within the peripheral nervous system. Beyond supporting neuronal growth, NTRK1 contributes to injury responses, helping facilitate neuronal repair and regeneration. Dysregulation or mutations in NTRK1 have been implicated in neurodegenerative diseases, such as Charcot-Marie-Tooth disease, as well as in certain cancers, making it a significant target for therapeutic research and drug development efforts.

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