Tripartite Motif-Containing Protein 72 (TRIM72) Antibody
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Description
Tripartite Motif-Containing Protein 72 (TRIM72) Antibody is a Rabbit Polyclonal antibody for the detection of TRIM72.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tripartite Motif-Containing Protein 72 (TRIM72) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/50 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6ZMU5 |
| Gene ID | 493829 |
| Background | Antibody anti-TRIM72 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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TRIM72 antibody
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Tripartite Motif-Containing Protein 72 (TRIM72) Antibody
TRIM72 is a muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca (2+) dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
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Tripartite Motif-Containing Protein 72 (TRIM72) Antibody
Tripartite Motif-Containing Protein 72 (TRIM72) Antibody is a Rabbit Polyclonal antibody for the detection of TRIM72.
Ver Producto