Transmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2) Antibody

Este producto es parte de TMIGD - transmembrane and immunoglobulin domain containing
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169€ (20 µg)

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935106861
info@markelab.com
name
Transmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302311
tested applications
ELISA, IHC, IF/ICC

Description

TMIGD2 Antibody is a Rabbit Polyclonal against TMIGD2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetTransmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2)
HostRabbit
ReactivityHuman
Recommended DilutionIHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ96BF3
Gene ID126259
NCBI AccessionNP_001162597.1, NM_001169126.1, NP_001295161.1, NM_001308232.1, NP_653216.2, NM_144615.2
OMIM614715
AliasCD28H,IGPR1,IGPR-1,Immunoglobulin and proline-rich receptor 1,CD28 homolog
BackgroundAntibody anti-TMIGD2
StatusRUO

Descripción

TMIGD2 (Transmembrane and Immunoglobulin Domain Containing 2) is associated with immune modulation and endothelial cell interactions. Expressed on certain immune cells and endothelial cells, TMIGD2 mediates adhesion and communication between these cellular populations. It has been identified as a co-stimulatory molecule that enhances T-cell responses during immune activation. TMIGD2 also contributes to vascular homeostasis by promoting endothelial integrity and facilitating leukocyte transmigration during inflammation. Dysregulation of TMIGD2 has been linked to immune dysregulation and inflammatory disorders, making it a potential target for therapeutic interventions in autoimmune diseases and vascular inflammation.

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