Transmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2) Antibody

169€ (20 µg)
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935106861
info@markelab.com
name
Transmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302311
tested applications
ELISA, IHC, IF/ICC
Description
TMIGD2 Antibody is a Rabbit Polyclonal against TMIGD2.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Transmembrane And Immunoglobulin Domain-Containing Protein 2 (TMIGD2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q96BF3 |
Gene ID | 126259 |
NCBI Accession | NP_001162597.1, NM_001169126.1, NP_001295161.1, NM_001308232.1, NP_653216.2, NM_144615.2 |
OMIM | 614715 |
Alias | CD28H,IGPR1,IGPR-1,Immunoglobulin and proline-rich receptor 1,CD28 homolog |
Background | Antibody anti-TMIGD2 |
Status | RUO |
Descripción
TMIGD2 (Transmembrane and Immunoglobulin Domain Containing 2) is associated with immune modulation and endothelial cell interactions. Expressed on certain immune cells and endothelial cells, TMIGD2 mediates adhesion and communication between these cellular populations. It has been identified as a co-stimulatory molecule that enhances T-cell responses during immune activation. TMIGD2 also contributes to vascular homeostasis by promoting endothelial integrity and facilitating leukocyte transmigration during inflammation. Dysregulation of TMIGD2 has been linked to immune dysregulation and inflammatory disorders, making it a potential target for therapeutic interventions in autoimmune diseases and vascular inflammation.
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