Translocon-Associated Protein Subunit Beta (SSR2) Protein

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Description
SSR2 is a recombinant protein.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | SSR2 |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P43308 |
| Background | Protein SSR2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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TRAPB(translocon-associated protein subunit beta), also known as SSR2(signal sequence receptor subunit beta), is a 22-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum(ER)(PMID: 7789174). It is a part of the tetrameric TRAP complex(TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins(PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation(ERAD)(PMID: 17380188).
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The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].
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