SSR2 antibody
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Description
TRAPB(translocon-associated protein subunit beta), also known as SSR2(signal sequence receptor subunit beta), is a 22-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum(ER)(PMID: 7789174). It is a part of the tetrameric TRAP complex(TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins(PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation(ERAD)(PMID: 17380188).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | signal sequence receptor, beta(translocon-associated protein beta) (SSR2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 24 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, FC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P43308 |
| Alias | Translocon-associated protein subunit beta (TRAP-beta),Signal sequence receptor subunit beta (SSR-beta),SSR2,TRAPB |
| Background | Antibody anti-SSR2 |
| Status | RUO |
| Note | Mol. Weight 24 kDa |
Descripción
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TRAPB(translocon-associated protein subunit beta), also known as SSR2(signal sequence receptor subunit beta), is a 22-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum(ER)(PMID: 7789174). It is a part of the tetrameric TRAP complex(TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins(PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation(ERAD)(PMID: 17380188).
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The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].
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