Transcriptional Adaptor 3 (TADA3L) Antibody
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Description
Transcriptional Adaptor 3 (Ngg1 Homolog, Yeast)-Like Antibody is a Rabbit Polyclonal antibody against Transcriptional Adaptor 3 (Ngg1 Homolog, Yeast)-Like.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transcriptional Adaptor 3 (TADA3L) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75528 |
| Gene ID | 10474 |
| NCBI Accession | NP_001265199.1, NM_001278270.1 |
| OMIM | 602945 |
| Background | Antibody anti-TADA3L |
| Status | RUO |
Descripción
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Transcriptional Adaptor 3 (TADA3L) Antibody
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
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