Transcription Factor 4 (TCF4) Antibody
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Description
TCF4 Antibody is a Rabbit Polyclonal antibody against TCF4. This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described.Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transcription Factor 4 (TCF4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15884 |
| Gene ID | 6925 |
| NCBI Accession | NP_003190.1 |
| Background | Antibody anti-TCF4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Human TCF4 (Transcription factor 4) ELISA Kit
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TCF4 antibody
Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box(5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element(SSTR2-INR) to activate transcription(By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.
Ver ProductoTCF4 antibody
Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box(5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element(SSTR2-INR) to activate transcription(By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.
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