TRAF3-interacting JNK-activating modulator (TRAF3IP3) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
TRAF3-interacting JNK-activating modulator (TRAF3IP3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211716
tested applications
ELISA, WB, IHC
Description
TRAF3IP3 Antibody is a Rabbit Polyclonal against TRAF3IP3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TRAF3-interacting JNK-activating modulator (TRAF3IP3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, WB: 1/200 - 1/1000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y228 |
| Gene ID | 80342 |
| Alias | T3JAM,TRAF3-interacting protein 3 |
| Background | Antibody anti-TRAF3IP3 |
| Status | RUO |
Descripción
TRAF3-interacting JNK-activating modulator (TRAF3IP3) is a protein involved in the activation of the c-Jun N-terminal kinase (JNK) signaling pathway, a key regulator of cell stress responses, apoptosis, and immune function. TRAF3IP3 acts as a scaffold that facilitates the recruitment of TRAF proteins and kinases to specific signaling complexes, promoting JNK activation in response to stimuli such as cytokines and stress. It is also involved in modulating immune receptor signaling and contributes to both innate and adaptive immune responses. Dysregulation of TRAF3IP3 expression or function can affect immune homeostasis and has been linked to immune disorders and inflammatory diseases, where excessive JNK activity may drive pathological processes. Emerging studies suggest its potential role in cancer biology, where JNK signaling contributes to tumor growth or suppression depending on the cellular context.
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