TRAF-Interacting Protein With FHA Domain-Containing Protein A (TIFA) Antibody
292.5€ (80 µl)
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935106861
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name
TRAF-Interacting Protein With FHA Domain-Containing Protein A (TIFA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034432
tested applications
ELISA, WB
Description
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: TRAF-Interacting Protein With FHA Domain-Containing Protein A (TIFA) Immunogen: KLH-conjugated synthetic peptide between 52-79 amino acids from the N-terminal region of human TIFA. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 21.4 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96CG3 |
| Background | Antibody anti-TIFA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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TRAF-Interacting Protein With FHA Domain-Containing Protein A (TIFA) Antibody
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
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