Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) Antibody
195€ (20 µl)
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Name
Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001586
Tested Applications
ELISA, IHC
Description
TIRAP Antibody is a Rabbit Polyclonal antibody against TIRAP. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1.25 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 24 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P58753-1 |
| Gene ID | 114609 |
| NCBI Accession | NP_001034750.1 |
| Background | Antibody anti-TIRAP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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