Toll Like Receptor 2 (TLR2) Antibody (PE)
520€ (100 tests)
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935106861
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name
Toll Like Receptor 2 (TLR2) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx414263
tested applications
FCM
Description
Toll-Like Receptor 2 (CD282) Antibody (PE) is a Mouse Monoclonal antibody against Toll-Like Receptor 2 (CD282).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Toll Like Receptor 2 (TLR2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 100 tests |
| Form | Lyophilized |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C or -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60603 |
| Gene ID | 7097 |
| NCBI Accession | NP_003255.2 |
| OMIM | 246300 |
| Alias | Toll-like receptor 2,TIL4,CD282,Toll/interleukin-1 receptor-like protein 4 |
| Background | Antibody anti-TLR2 |
| Status | RUO |
Descripción
Toll-like receptor 2 (TLR2) is an essential component of the innate immune system, known for its role in recognizing and responding to pathogen-associated molecular patterns (PAMPs). TLR2 is part of the toll-like receptor (TLR) family, which detects structural components specific to pathogens and activates immune responses. TLR2 is particularly versatile, recognizing a broad array of ligands from bacteria, fungi, and viruses, and functions primarily by forming heterodimers with other TLRs, specifically TLR1 and TLR6. These heterodimers expand TLR2’s range of ligand recognition, including lipoproteins, lipopeptides, peptidoglycan, and lipoteichoic acid, enabling it to respond effectively to both Gram-positive and Gram-negative bacteria. The expression of TLR2 is predominantly found in immune cells such as macrophages, dendritic cells, and monocytes. TLR2’s activity is integral to the initiation of pro-inflammatory responses that support early immune defense. As such, it plays a pivotal role in the development of both innate and adaptive immunity by bridging the two responses through cytokine release and antigen presentation. Due to its broad functionality and critical role in immunity, TLR2 has become a focus for research into infections, inflammation, and immune-related diseases, as well as a potential target for immunotherapy.
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