Loading...
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Cell ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
493.75€ (96 tests)
Elisa Kits CD40
proveedor
Abbexareference
abx595105Tested Applications
ELISAreactivity
Human, Mousestatus
RUOclonality
Descripción
CD40 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Background
CD40 is a co-stimulatory protein primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells (DCs), macrophages, and certain types of endothelial cells. This molecule plays a critical role in both innate and adaptive immune responses. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, specifically classified as TNFRSF5. CD40 is essential for initiating and sustaining immune responses, particularly by interacting with its ligand, CD40L (CD154), which is predominantly expressed on activated T cells. The CD40-CD40L interaction is a central element in immune regulation, providing necessary signals for B cell activation, differentiation, and class switching during antibody responses. Furthermore, CD40 signaling influences macrophage activation, dendritic cell maturation, and cytokine production, all of which are crucial for orchestrating immune responses.
Características del producto
category
ELISA Kits
immunogen target
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40)
reactivity
Human, Mouse
detection method
Colorimetric
sample type
Cell ELISA
size 1
96 tests
alias
p50,Bp50,CDW40,TNFRSF5,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,CDw40,CD40
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD40
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human TNFRSF5/CD40(Tumor necrosis factor receptor superfamily member 5) ELISA Kit
proveedor
FineTestreference
EH0311reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse CD40(B-cell surface antigen CD40) ELISA Kit
proveedor
FineTestreference
EM1903reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- CD40 antibody
proveedor
FineTestreference
FNab01477Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalReceptor for TNFSF5/CD40LG. Transduces TRAF6-and MAP3K8-mediated signals that activate ERK in macrophages and B cells, l...
Precio a consultar
Ver más