935106861
info@markelab.com
Precio
250€ (50 µl)
CD40 Antibody is a Rabbit Polyclonal against CD40.
CD40 is a co-stimulatory protein primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells (DCs), macrophages, and certain types of endothelial cells. This molecule plays a critical role in both innate and adaptive immune responses. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, specifically classified as TNFRSF5. CD40 is essential for initiating and sustaining immune responses, particularly by interacting with its ligand, CD40L (CD154), which is predominantly expressed on activated T cells. The CD40-CD40L interaction is a central element in immune regulation, providing necessary signals for B cell activation, differentiation, and class switching during antibody responses. Furthermore, CD40 signaling influences macrophage activation, dendritic cell maturation, and cytokine production, all of which are crucial for orchestrating immune responses.
Primary Antibodies
Polyclonal
Human, Mouse
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40)
Rabbit
Unconjugated
Liquid
ELISA, IHC
Antigen Affinity Chromatography.
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
50 µl
100 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
CD40
No
Shipped within 5-10 working days.
p50,Bp50,CDW40,TNFRSF5,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,CDw40,CD40
This product is for research use only.
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