TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx129469
Tested Applications
WB
Description
Tumor Necrosis Factor Receptor Superfamily, Member 5 Antibody is a Rabbit Polyclonal against Tumor Necrosis Factor Receptor Superfamily, Member 5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Immunogen: TNFRSF5 (Cys26-Arg193) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27512 |
| Alias | p50,Bp50,CDW40,TNFRSF5,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,CDw40,CD40 |
| Background | Antibody anti-CD40 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD40 is a co-stimulatory protein primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells (DCs), macrophages, and certain types of endothelial cells. This molecule plays a critical role in both innate and adaptive immune responses. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, specifically classified as TNFRSF5. CD40 is essential for initiating and sustaining immune responses, particularly by interacting with its ligand, CD40L (CD154), which is predominantly expressed on activated T cells. The CD40-CD40L interaction is a central element in immune regulation, providing necessary signals for B cell activation, differentiation, and class switching during antibody responses. Furthermore, CD40 signaling influences macrophage activation, dendritic cell maturation, and cytokine production, all of which are crucial for orchestrating immune responses.
Productos relacionados
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Antibody
CD40 Antibody is a Rabbit Polyclonal antibody against CD40. This gene is a member of the TNF-receptor superfamily. The e…
Ver producto
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Antibody
CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been…
Ver producto
TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) Antibody
Rabbit polyclonal antibody against CD40 protein. Immunogen region is C-terminal.…
Ver producto