Thyroid Hormone Receptor Associated Protein 3 (THRAP3) Antibody

Product Graph
195€ (20 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Thyroid Hormone Receptor Associated Protein 3 (THRAP3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx124123
tested applications
ELISA, WB, IHC

Description

THRAP3 Antibody is a Rabbit Polyclonal Antibody against THRAP3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Thyroid Hormone Receptor Associated Protein 3 (THRAP3)
Immunogen: Recombinant protein corresponding to THRAP3. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 109 kDa  Observed MW: 150 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y2W1
Gene ID
9967
NCBI Accession
NP_005110.2
Background
Antibody anti-THRAP3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

FNab08673

THRAP3 antibody

Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex(EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons(PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes(PubMed:24043798).

Ver Producto
abx028840

Thyroid Hormone Receptor Associated Protein 3 (THRAP3) Antibody

THRAP3 plays a role in transcriptional coactivation.

Ver Producto
abx124123

Thyroid Hormone Receptor Associated Protein 3 (THRAP3) Antibody

THRAP3 Antibody is a Rabbit Polyclonal Antibody against THRAP3.

Ver Producto