Thiopurine Methyltransferase (TPMT) Antibody

819€ (1 ml)
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935106861
info@markelab.com
name
Thiopurine Methyltransferase (TPMT) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx174750
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Thiopurine Methyltransferase (TPMT) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Purification | Purified by Protein A and Protein G affinity chromatography. |
Size 1 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Please enquire. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Background | Antibody anti-TPMT |
Status | RUO |
Descripción
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Thiopurine S-Methyltransferase (TPMT) Antibody
TPMT Antibody is a Rabbit Polyclonal antibody against TPMT. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
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