TPMT antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
TPMT antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08893
tested applications
ELISA, WB, IHC, IF
Description
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | thiopurine S-methyltransferase (TPMT) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 28-32 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P51580 |
| Gene ID | 7172 |
| Alias | Thiopurine S-methyltransferase,Thiopurine methyltransferase,TPMT |
| Background | Antibody anti-TPMT |
| Status | RUO |
| Note | Mol. Weight 28-32 kDa |
Descripción
Related Products
Human TPMT (Thiopurine S-methyltransferase) ELISA Kit
Ver Producto
Thiopurine S-Methyltransferase (TPMT) Antibody
TPMT Antibody is a Rabbit Polyclonal antibody against TPMT. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
Ver Producto