TGF-beta 2-Specific Antibody
377€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
TGF-beta 2-Specific Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx238639
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
TGF-beta 2-Specific Antibody is a Rabbit Polyclonal against TGF-beta 2-Specific.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: TGF-beta 2-Specific Immunogen: transforming growth factor, beta 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 44 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61812 |
| Alias | G-TSF,LDS4,TGF-beta2,Cetermin,Glioblastoma-derived T-cell suppressor factor |
| Background | Antibody anti-TGFB2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TGFB2 is a member of the TGF-β cytokine family, which regulates a wide range of cellular processes, including proliferation, differentiation, migration, apoptosis, and immune suppression. TGFB2 is critically involved in embryogenesis, particularly in the development of the heart, lungs, and central nervous system, as well as in tissue homeostasis and repair. It signals through SMAD-dependent and non-SMAD pathways, modulating gene expression and cellular responses to environmental stimuli. TGFB2 plays an essential role in immune regulation, where it suppresses inflammation and promotes tolerance by inducing regulatory T cell (Treg) development. Dysregulation of TGFB2 is implicated in developmental disorders, fibrosis, and tumor progression, where it drives epithelial-mesenchymal transition (EMT) and facilitates immune evasion. Knockout studies show severe developmental defects, including cardiac abnormalities, craniofacial malformations, and impaired organogenesis, underscoring TGFB2’s importance in tissue development, immune modulation, and homeostatic maintenance.
Productos relacionados
Transforming Growth Factor Beta-2 (TGFB2) Antibody
Rabbit polyclonal antibody against TGF beta 2 protein. Immunogen region is C-terminal.…
Ver producto
Transforming Growth Factor Beta 2 (TGFB2) Antibody
This product is currently in development. The lead time for this product may be several months. Please contact us at…
Ver producto
Transforming Growth Factor Beta 2 (TGFB2) Antibody
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional …
Ver producto