Tetraspanin-7 (TSPAN7) Antibody

Este producto es parte de TSPAN7 - tetraspanin 7
Tetraspanin-7 (TSPAN7) Antibody

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µg)

Antibody anti-TSPAN7

proveedor

Abbexa

reference

abx110260

Tested Applications

ELISA, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Tetraspanin-7 Antibody is a Rabbit Polyclonal antibody against Tetraspanin-7.


Background

Tetraspanin 7 (TSPAN7) is a member of the tetraspanin superfamily, a group of membrane proteins involved in various cellular functions such as signaling, adhesion, and intracellular trafficking. Tetraspanins are characterized by their distinctive structure, containing four transmembrane domains. TSPAN7 is primarily expressed in the central nervous system, particularly in neurons, and is also found in certain immune cells. TSPAN7 is of interest due to its involvement in neurological processes and its role in neurodevelopmental disorders, most notably X-linked intellectual disability (XLID). Mutations or dysregulation of TSPAN7 have been implicated in cognitive deficits, autism spectrum disorders, and other neurological conditions, highlighting its importance in normal brain function. The primary role of TSPAN7 appears to be in facilitating cell-cell interactions and maintaining synaptic function. Through its association with other proteins in the tetraspanin web—an organized network of tetraspanins and their partner proteins—TSPAN7 modulates cellular signaling pathways crucial for neuronal growth, differentiation, and communication. These functions make TSPAN7 essential for neural development and synaptic plasticity, processes that underlie learning and memory.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Tetraspanin-7 (TSPAN7)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IHC, IF/ICC


purity

> 95%


purification

Purified by Protein G.


recommended dilution

IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

TSPAN7


dry ice

No


availability

Shipped within 5-10 working days.


alias

Membrane component chromosome X surface marker 1,A15,MXS1,CD231, MRX58,CCG-B7,TM4SF2,XLID58,T-cell acute lymphoblastic leukemia-associated antigen 1,TALLA-1


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