Testis-Specific Y-Encoded Protein 3 (TSPY3) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Testis-Specific Y-Encoded Protein 3 (TSPY3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx239067
tested applications
ELISA, WB, IHC
Description
TSPY3 Antibody is a Rabbit Polyclonal against TSPY3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Testis-Specific Y-Encoded Protein 3 (TSPY3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/10000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0CV98 |
| Gene ID | 100289087 |
| Alias | CT78,TSPY,TSPY1,TSPY10,Testis-specific Y-encoded protein 3 |
| Background | Antibody anti-TSPY3 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Testis specific protein Y-linked 3 (TSPY3) is a gene within the TSPY family that is involved in the regulation of spermatogenesis and male fertility TSPY3 is specifically expressed in the testis, where it plays a key role in the development and maintenance of spermatogonial stem cells These stem cells are responsible for producing sperm throughout a male's life, making TSPY3 crucial for maintaining spermatogenesis by ensuring that germ cells proliferate and differentiate properly The exact mechanisms of TSPY3’s function are still under study, but it is believed to interact with other proteins and transcription factors that control germ cell differentiation and apoptosis to ensure proper cell survival and development during spermatogenesis Dysregulation of TSPY3 expression has been associated with infertility and testicular disorders, particularly in conditions where abnormal expression patterns contribute to testicular cancer and germ cell tumors where it may disrupt normal cellular regulation and promote tumorigenesis TSPY3’s regulatory role in maintaining male reproductive health, its impact on genomic stability, and its association with cancer highlight its importance in male fertility and in preventing reproductive system diseases
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