Testis-Specific Y-Encoded-Like Protein 1 (TSPYL1) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Testis-Specific Y-Encoded-Like Protein 1 (TSPYL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126746
tested applications
ELISA, WB, IHC, IP
Description
TSPYL1 Antibody is a Rabbit Polyclonal against TSPYL1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Testis-Specific Y-Encoded-Like Protein 1 (TSPYL1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/100 - 1/500, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H0U9 |
| Gene ID | 7259 |
| NCBI Accession | NP_003300.1 |
| Alias | TSPYL,TSPY-like protein 1,Testis-specific Y-encoded-like protein 1 |
| Background | Antibody anti-TSPYL1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
TSPY like 1 (TSPYL1) is a protein that shares homology with the testis-specific protein Y (TSPY) gene family, playing a role in regulating gene expression and cellular differentiation TSPYL1 is involved in cellular processes such as cell cycle regulation, apoptosis, and DNA repair It has been shown to participate in modulating transcription by interacting with other regulatory proteins and affecting chromatin dynamics TSPYL1's expression is particularly prominent in testicular tissue, but it is also found in other tissues, where it may contribute to the regulation of cell proliferation and differentiation In the context of cancer, TSPYL1 has been implicated as a tumor suppressor, where its loss or downregulation may promote tumor growth and metastasis Recent studies suggest that TSPYL1’s role in DNA repair and stress responses may help protect against genomic instability, further emphasizing its importance in maintaining cellular function and preventing cancer development TSPYL1 could serve as a potential biomarker for certain cancers and a target for therapeutic strategies aimed at restoring its function to suppress tumor growth
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