Telomerase Reverse Transcriptase (TERT) Antibody
Pida mas información
935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-TERT
proveedor
Abbexareference
abx110254Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Telomerase reverse transcriptase Antibody is a Rabbit Polyclonal antibody against Telomerase reverse transcriptase.
Background
Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Telomerase Reverse Transcriptase (TERT)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purity
> 95%
purification
Purified by Protein G.
recommended dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
TERT
dry ice
No
availability
Shipped within 5-10 working days.
alias
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2
uniprot id
NCBI accession
NP_001180305.1, NM_001193376.1
Quizá le pueda interesar
Human TERT(Telomerase reverse transcriptase) ELISA Kit
proveedor
FineTestreference
EH2120reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Tert(Telomerase reverse transcriptase) ELISA Kit
proveedor
FineTestreference
EM0730reactivity
mousestatus
RUOPrecio a consultar
Ver másRat TERT(Telomerase reverse transcriptase) ELISA Kit
proveedor
FineTestreference
ER2133reactivity
ratstatus
RUOPrecio a consultar
Ver más