Telomerase Reverse Transcriptase (TERT) Antibody
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935106861
info@markelab.com
Precio
299€ (100 µl)
Antibody anti-TERT
proveedor
Abbexareference
abx103376Tested Applications
WB, IHC, IF/ICCreactivity
Ratstatus
RUOclonality
PolyclonalDescripción
Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT).
Background
Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Rat
immunogen target
Telomerase Reverse Transcriptase (TERT)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
recommended dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
100 µl
size 2
200 µl
size 3
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
TERT
dry ice
No
availability
Shipped within 5-7 working days.
alias
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2
uniprot id
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