Telomerase Reverse Transcriptase (TERT) Antibody

Este producto es parte de TERT - Telomerase Reverse Transcriptase
Telomerase Reverse Transcriptase (TERT) Antibody

Pida mas información

935106861

info@markelab.com

Precio

299€ (100 µl)

Antibody anti-TERT

proveedor

Abbexa

reference

abx103376

Tested Applications

WB, IHC, IF/ICC

reactivity

Rat

status

RUO

clonality

Polyclonal

Descripción

Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT).


Background

Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Rat


immunogen target

Telomerase Reverse Transcriptase (TERT)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC, IF/ICC


purification

Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.


recommended dilution

WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.


size 1

100 µl


size 2

200 µl


size 3

1 ml


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

TERT


dry ice

No


availability

Shipped within 5-7 working days.


alias

CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2


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