Telomerase Reverse Transcriptase (TERT) Antibody
442€ (200 µl)
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935106861
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name
Telomerase Reverse Transcriptase (TERT) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433353
tested applications
P-ELISA, WB, IF/ICC, FCM
Description
Telomerase Reverse Transcriptase (TERT) Antibody is a Goat Polyclonal antibody against Telomerase Reverse Transcriptase (TERT).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Telomerase Reverse Transcriptase (TERT) Immunogen: abx616732 - Internal region, 597-611 AA: C-QLRELSEAEVRQHRE |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000, WB: 1 µg/ml, IF/ICC: 10 µg/ml, FCM: 10 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IF/ICC, FCM |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 7015 |
| NCBI Accession | NP_937983.2, NP_001180305.1 |
| Alias | CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2 |
| Background | Antibody anti-TERT |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.
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