Telomerase Reverse Transcriptase (TERT) Antibody
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-TERT
proveedor
Abbexareference
abx433353Tested Applications
P-ELISA, WB, IF/ICC, FCMreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Telomerase Reverse Transcriptase (TERT) Antibody is a Goat Polyclonal antibody against Telomerase Reverse Transcriptase (TERT).
Background
Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Telomerase Reverse Transcriptase (TERT)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB, IF/ICC, FCM
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/32000, WB: 1 µg/ml, IF/ICC: 10 µg/ml, FCM: 10 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
TERT
dry ice
No
availability
Shipped within 5-10 working days.
alias
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2
NCBI accession
NP_937983.2, NP_001180305.1
note
Concentration: 0.5 mg/ml -
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