Taste 2 Receptor Member 8 (TAS2R8) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Taste 2 Receptor Member 8 (TAS2R8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015486
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against TAS2R8 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Taste 2 Receptor Member 8 (TAS2R8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NYW2 |
| Alias | TAS2R8,T2R8,taste receptoR type 2 member 8,TRB5 |
| Background | Antibody anti-TAS2R8 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
TAS2R8 is another member of the TAS2R family of taste receptors, specifically involved in detecting bitter compounds. This receptor is expressed in the taste buds and is particularly sensitive to certain bitter chemicals. When TAS2R8 binds to its ligands, it initiates signaling pathways that result in the perception of bitterness. TAS2R8, like other bitter receptors, is thought to function as part of a protective mechanism, alerting individuals to the presence of potentially harmful or toxic substances. The variation in TAS2R8's response to different bitter compounds is due to genetic factors that influence the receptor's sensitivity. People with heightened sensitivity to TAS2R8 may have stronger aversions to certain bitter foods, such as vegetables, and may exhibit distinct dietary preferences. Research into TAS2R8 helps us understand how genetic variation in taste receptors can affect food choices and the potential development of dietary interventions for those with altered taste sensitivities.
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