Taste 1 Receptor Member 3 (TAS1R3) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Taste 1 Receptor Member 3 (TAS1R3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028771
tested applications
ELISA, WB
Description
The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Taste 1 Receptor Member 3 (TAS1R3) Immunogen: KLH-conjugated synthetic peptide between 229-258 amino acids from the N-terminal region of human TAS1R3. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 93.4 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7RTX0 |
| Alias | TAS1R3,sweet taste receptor T1R3,taste receptor,Sac |
| Background | Antibody anti-TAS1R3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
TAS1R3 is another critical component of the type 1 taste receptor family, primarily involved in the perception of sweet and umami tastes. TAS1R3 partners with TAS1R1 and TAS1R2 to form functional receptor complexes responsible for detecting specific taste qualities. When combined with TAS1R1, TAS1R3 contributes to the perception of umami, while in combination with TAS1R2, it plays a key role in the detection of sweet tastes. TAS1R3 is expressed in taste receptor cells on the tongue and plays a significant role in the brain's ability to interpret taste signals, especially for sugars and amino acids. The activation of TAS1R3 by its ligands leads to signaling cascades that involve second messengers, which ultimately result in the sensation of sweetness or umami. TAS1R3’s role in both sweet and savory taste perception makes it essential for the regulation of food preferences and nutritional intake. Variations in TAS1R3 expression or function are linked to individual differences in taste preferences and dietary habits.
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