Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015760
tested applications
ELISA, WB, FCM
Description
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate.It is the most basic of the acid phosphatases and is the only form not inhibited by L (+)-tartrate.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 54, 11433, 25732, 397414 |
| Alias | HPAP,TRACP5a,TRACP5b,TRAP,TRAcP,TrATPase |
| Background | Antibody anti-ACP5 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Acid phosphatases (ACP) are a group of enzymes that catalyze the hydrolysis of phosphate ester bonds under acidic conditions, resulting in the release of inorganic phosphate from organic molecules. These enzymes are characterized by their ability to function optimally at low pH levels. There are multiple forms of acid phosphatase, often denoted as ACP1, ACP2, ACP3, ACP4, and ACP5. Each isoform may have distinct tissue distribution, substrate specificity, and physiological roles. ACP1. It is found in various tissues and body fluids, including red blood cells, bone, prostate gland, and semen. It is a biomarker for poor prognosis in prostate cancer has been linked to bad clinical prognosis. ACP5 (Tartrate-Resistant Acid Phosphatase - TRAP) is mainly found in bone tissue, particularly in osteoclasts and Involved in bone resorption by osteoclasts, playing a critical role in bone remodeling and calcium homeostasis
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