Tapasin (TAPBP) Antibody

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Description
Tapasin Antibody is a Rabbit Polyclonal against Tapasin.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Tapasin (TAPBP) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Isotype | IgG |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol and 0.01% sodium azide. |
Availability | Shipped within 7-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15533, Q9R233 |
Gene ID | 6892, 21356 |
OMIM | 601962 |
Background | Antibody anti-TAPBP |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Tapasin (TAPBP) Antibody
TAPBP Antibody is a Rabbit Polyclonal antibody against TAPBP. This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
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Tapasin (TAPBP) Antibody
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
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