T-Lymphocyte Activation Antigen CD86 (CD86) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
T-Lymphocyte Activation Antigen CD86 (CD86) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421524
tested applications
FCM
Description
T-Lymphocyte Activation Antigen CD86 (CD86) Antibody is a Rat Monoclonal antibody for the detection of T-Lymphocyte Activation Antigen CD86 (CD86) in Mouse samples.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Lymphocyte Activation Antigen CD86 (CD86) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Clone ID | O220 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42082 |
| Gene ID | 12524 |
| NCBI Accession | NP_062261.3 |
| Alias | B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86 |
| Background | Antibody anti-CD86 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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anti- CD86 antibody
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
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