T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody (PE / Cyanine 7)
156€ (50 tests)
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Name
T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody (PE / Cyanine 7)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx228075
Tested Applications
FCM
Description
CD86 antibody (PE / Cyanine 7) is a Rat monoclonal antibody against CD86.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) |
| Host | Rat |
| Reactivity | Mouse |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/782 |
| Clonality | Monoclonal |
| Conjugation | PE / Cyanine 7 |
| Isotype | IgG2a |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P42082 |
| Gene ID | 12524 |
| Alias | B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80 |
| Background | Antibody anti-CD80 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
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