T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody (FITC)

429€ (100 µg)
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935106861
info@markelab.com
name
T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx414230
tested applications
FCM
Description
Cluster of Differentiation 86 (CD86) Antibody (FITC) is a Rat Monoclonal antibody against Cluster of Differentiation 86 (CD86).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) |
Host | Rat |
Reactivity | Mouse |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | FITC |
Isotype | IgG2b |
Purification | Purified |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | FCM |
Buffer | PBS, 1% BSA. Contains sodium azide. |
Availability | Shipped within 3-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P42082 |
Alias | B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86 |
Background | Antibody anti-CD86 |
Status | RUO |
Note | Concentration: 0.1 mg/ml - |
CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.
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