T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody
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935106861
info@markelab.com
Precio
494€ (200 µg)
Antibody anti-CD86
proveedor
Abbexareference
abx412768Tested Applications
IHC, FCM, IPreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
Cluster of Differentiation 86 (CD86) Antibody is a Mouse Monoclonal antibody against Cluster of Differentiation 86 (CD86).
Background
CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86)
host
Mouse
isotype
IgG1
conjugation
Unconjugated
form
Liquid
tested applications
IHC, FCM, IP
purification
Purified
recommended dilution
Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS. Contains sodium azide.
size 1
200 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD86
dry ice
No
availability
Shipped within 3-7 working days.
alias
B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
uniprot id
note
Concentration: 1.0 mg/ml -
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