T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody

Este producto es parte de CD86 molecule
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494€ (200 µg)

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935106861
info@markelab.com
name
T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx412768
tested applications
IHC, FCM, IP

Description

Cluster of Differentiation 86 (CD86) Antibody is a Mouse Monoclonal antibody against Cluster of Differentiation 86 (CD86).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetT-Lymphocyte Activation Antigen CD86 / B7-2 (CD86)
HostMouse
ReactivityHuman
Recommended DilutionValidated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
IsotypeIgG1
PurificationPurified
Size 1200 µg
FormLiquid
Tested ApplicationsIHC, FCM, IP
BufferPBS. Contains sodium azide.
AvailabilityShipped within 3-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP42081
AliasB70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
BackgroundAntibody anti-CD86
StatusRUO
NoteConcentration: 1.0 mg/ml -

Descripción

CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.

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