T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody (FITC)
364€ (100 tests)
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935106861
info@markelab.com
name
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx139224
tested applications
FCM
Description
CD80 Antibody is a Mouse Monoclonal against CD80.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-lymphocyte activation antigen CD80 / B7-1 (CD80) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 20 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (2 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 |
| Clone ID | Y873 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P33681 |
| Gene ID | 941 |
| Alias | B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80 |
| Background | Antibody anti-CD80 |
| Status | RUO |
Descripción
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
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