T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
377€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx239881
Tested Applications
ELISA, WB, IHC
Description
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody is a Mouse Monoclonal antibody for the detection of CD80.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-lymphocyte activation antigen CD80 / B7-1 (CD80) Immunogen: CD80 |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/1000 - 1/4000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | Observed MW: 60 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P33681 |
| Gene ID | 941 |
| OMIM | 112203 |
| Alias | B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80 |
| Background | Antibody anti-CD80 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
Productos relacionados
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a…
Ver producto
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
T-lymphocyte activation antigen CD80 (CD80) Antibody is a Mouse Monoclonal antibody against T-lymphocyte activation anti…
Ver producto
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
CD80 Antibody is a Rabbit Polyclonal antibody against Human.…
Ver producto