T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) Antibody

Descripción

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, FCM

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

CD8B

dry ice

availability

Shipped within 5-10 working days.

alias

LY3,P37,LEU2,LYT3,Ly-3,CD8B1,CD8beta,T-cell surface glycoprotein CD8 beta chain

uniprot id

https://www.uniprot.org/uniprotkb/P10966

note

This product is for research use only.

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anti- CD8B antibody

proveedor

FineTest

reference

FNab01506

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in...

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