T-Cell Surface Glycoprotein CD4 (CD4) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
T-Cell Surface Glycoprotein CD4 (CD4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015800
tested applications
ELISA
Description
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells.This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily.It is responsible for the recognition of the MHC class II antigen.The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell Surface Glycoprotein CD4 (CD4) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4 |
| Background | Antibody anti-CD4 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
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