T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (PerCP / Cyanine 5.5)
598€ (100 tests)
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Name
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (PerCP / Cyanine 5.5)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx347100
Tested Applications
FCM
Description
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (PerCP / Cyanine 5.5) is a Mouse Monoclonal against T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | PerCP / Cyanine 5.5 |
| Isotype | IgG2a |
| Clone ID | R606 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P07766 |
| Gene ID | 916 |
| Alias | T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain |
| Background | Antibody anti-CD3E |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.
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